Potyviral NIa Proteinase, a Proteinase with Novel Deoxyribonuclease Activity
نویسندگان
چکیده
منابع مشابه
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity.
The NIa proteinase from pepper vein banding virus (PVBV) is a sequence-specific proteinase required for processing of viral polyprotein in the cytoplasm. It accumulates in the nucleus of the infected plant cell and forms inclusion bodies. The function of this protein in the nucleus is not clear. The purified recombinant NIa proteinase was active, and the mutation of the catalytic residues His-4...
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1976) which is a defective in killer toxin secretion and in secretion of mature a-factor (T. Achstetter & D. H. Wolf, unpublished work). With the aid of the two model substrates, Cbz-Tyr-Lys and Cbz-Tyr-Lys-Arg, we also found carboxypeptidase activity in the membrane fraction, which is able to remove the two amino acids lysine and arginine and may thus be involved in further processing of the a...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m404135200